ABSTRACT
Objective. Toassess national vaccination coverage, adverse events following immunization (AEFI) and evaluate the vaccination status in COVID infected patients. Methods. Sociodemographic data on vaccination and clinical characteristics of Covid-19 cases were extracted from the national COVID-19databases of the Public Health Emergency Center and the Expanded Program on Immunization. Result. A total number of 808229 out of 27 869965 (2.9%) were fully immunized on 13 February 2022 in the Cameroon. The most requested vaccine was Janssen with 48.24% of total doses administered. Women were less vaccinated than men and with a remarkable disparity in northern regions of the country. The Adamawa region presented the best performance 11.3% of adults fully immunized. Despite vaccinal coverage still insufficient among health care worker, they were the most vaccinated among priority groups (43.4%). Only 8% COVID-19 cases were vaccinated and 0.22 % of all vaccinated still developed COVID-19. Tolerability assessment identified 1.83 non-serious AEFI and 0.1 serious AEFI per 1000 doses administered. Only 7% of vaccinated individual still developed laboratory-confirmed COVID-19. Conclusion. COVID-19vaccination coverage is still low in Cameroon compared to the target of 60%. Although data completeness is still an issue, the protection against severe forms of the disease provided by the vaccines currently used is quite satisfactory. There is however a need to intensify all strategies to make people adhere to vaccination in order to protectthem against severe form of the disease.